Corporate Office- South Bend, IN

17187 State Road 23 South Bend, IN 46635 Phone: (574) 273-6000 Fax: (574) 247-8199 View Map & Get Directions

Elkhart, IN

1612 W. Lexington Ave. Elkhart, IN 46514 Phone: (574) 522-2273 Fax: (574) 522-4563 View Map & Get Directions

Plymouth, IN

1920 W. Lake Ave. Plymouth, IN 46563 Phone: (574) 941-4444 Fax: (574) 941-4440 View Map & Get Directions

Michigan City, IN

3219 South Franklin Street Michigan City, IN 46360 Phone: (219) 872-1000 Fax: (219) 879-1917 View Map & Get Directions

St. Joseph's Regional Medical Center, Medical Office Building

611 E. Douglas Road, Suite 124 Mishawaka, IN 46545 Phone: 574-247-8100 Fax: 574-855-2475 View Map & Get Directions

Health Issues

Amyotrophic lateral sclerosis (ALS) Symptoms and Types The symptoms at the onset of ALS may be so slight that they are frequently overlooked. Some of the most common symptoms include following:

• muscle weakness in the hands, arms, legs or the muscles of speech, swallowing or breathing
• twitching and cramping of muscles, especially those in the hands and feet
• loss of the use of the arms and legs
• difficulty in projecting the voice and "thick speech"
• shortness of breath, difficulty in breathing and swallowing are common in more advanced stages

Although there are many commonalities, symptoms will vary from person to person. Common tell-tale signs may be tripping or stumbling, trouble lifting, uncontrollable periods of laughing or crying or slurred speech. Progressive muscle weakness and paralysis are experienced by all people with the disease and the hands and feet are usually affected first.

Most of the weakening of the muscles starts on the trunk of the body, but will eventually begin to affect speech, swallowing, chewing and breathing. When the breathing muscles become affected, the patient will need a ventilator to breathe.
Unlike some other neuromuscular diseases, the person’s sense of sight, touch, hearing, taste and smell are not affected.

There are three classifications of ALS:

• Sporadic - the most common form of ALS in the United States accounting for 90 to 95% of all cases.
• Familial - occurring more than once in a family lineage. This accounts for a 5 to 10% of all cases in the U.S. but there is a 50% chance each offspring of a parent with ALS will inherit the gene mutation and may develop the disease.
• Guamanian – found in people of Guam and the Trust Territories of the Pacific in the 1950's.